-

News Bulletin

“Subscribe to NewsLetter”

“Subscribe to News Letter”

New Medicine

Card image cap
Delhi doctors treat 1.5-month-old baby with a hole in the heart
Bhaskar Live

The baby was brought to Fortis Escorts Heart Institute, Okhla, in a serious condition with breathing difficulties, sepsis-like symptoms, heart failure signs, elevated heart rate, excessive perspiration, inability to feed, liver enlargement, and failure to gain weight. An echocardiogram revealed that the baby suffered from a hole in the heart, also known as patent ductus arteriosus (PDA) — a condition where an extra blood vessel is found in babies before birth and just after birth.

Card image cap
In rare recovery, Kerala boy survives amoebic meningoencephalitis which has 97 percent mortality rate
Deccan Herald

Amidst concerns over the outbreak of deadly virus infections like Nipah in Kerala, the state on Monday reported a rare case of recovery from amoebic meningoencephalitis, which has a 97 percent mortality rate. State Health Minister Veena George's office on Monday confirmed that it was a rare occurrence, which has a mortality rate of 97 percent and it is believed that only 11 persons in the world so far recovered from the infection. Earlier detection of the infection helped in speedy recovery of the boy. The minister also praise the efforts of the medical team that treated the boy.

Card image cap
Scientists create first-ever 'Chimeroids' using cells from multiple people
Live Science

For the first time, scientists have grown 3D brain models using cells from multiple people. The new hybrid creations, which researchers have dubbed "chimeroids," are a variation of brain organoids — tiny 3D models made of tissue that mimic the structure and function of a full-size brain. These models are more accurate to human biology than 2D cellular models or animals like lab mice. Because of this, scientists hope that the models will accelerate drug research and development.

Card image cap
‘Placebo’ or ‘sham’ surgery is not a cruel trick – it can be very effective
The Conversation

Ten years ago, a scan showed that I had torn the meniscus in my knee. The pain was bad and I was limping a lot of the time. My doctor recommended arthroscopic knee surgery to fix it. Being scared of scalpels, I asked whether there were other options. He said I could try physiotherapy, but that it was unlikely to work. I tried the physio and did the recommended exercises diligently, and my knee pain and function returned to almost normal. I even ran my first (and only) marathon a year later.

Card image cap
AI’s healthcare solutions: From diagnosis to supplying meds
The Times of India

A small farmer from a remote village walks into the nearest town’s health clinic. He breathes into a tube connected to a Vionix analyser. This device compares the farmer’s breath with hundreds of millions of other samples from around the world. An AI model, running on the cloud, identifies patterns of disease manifestations in the spectral signatures of the breath sample and instantly provides results on the farmer’s smartphone.

Card image cap
Man who received first pig kidney transplant dies
BCC

The first man to receive a genetically modified pig kidney transplant has died two months after the operation, the hospital which carried out the procedure has said. Richard "Rick" Slayman, 62, was suffering with end-stage kidney disease before undergoing the operation in March. Massachusetts General Hospital (MGH) said on Sunday there was no indication his death was a result of the transplant.

Card image cap
Baby born deaf can hear after breakthrough gene therapy
Pharma Biz

A girl born deaf can now hear unaided after participating in a world-first trial. The CHORD study is for children born with hearing loss due to a genetic condition called auditory neuropathy. Auditory neuropathy is a condition where the ear can detect sound normally, but has a problem sending signals to the brain.

Card image cap
Researchers give more insight into hip osteoarthritis among older adults with spinal deformity
ANI News

A study found that one-third of patients receiving surgery for adult spinal deformity (ASD) also have severe hip osteoarthritis (OA), which can lead to poor spinal alignment and physical functionality. Findings of the study published in The Journal of Bone & Joint Surgery.

Card image cap
A new therapeutic target for traumatic brain injury
PR Newswire

For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, but they come with an amplified risk for developing dementia in the future. The glaring absence of treatments for such a widespread condition drove a team of scientists at Gladstone Institutes to uncover, on a molecular level, how traumatic brain injuries trigger neurodegeneration—and just as importantly, how to target that process to prevent long-term damage.

Global coverage

Card image cap
Sanofi begins phase 3 program for pneumococcal conjugate vaccine (PCV21); expands agreement with SK bioscience
Pharma Biz

Sanofi and SK bioscience have entered into a new chapter of their collaboration in pneumococcal vaccines with an expanded agreement to develop, license and commercialize next-generation PCVs for both pediatric and adult populations, reaffirming their commitment to fighting pneumococcal disease.

Card image cap
Drinking tea, coffee linked to lower risk of head and neck cancer: Study
The Tribune

Drinking tea or coffee is associated with a lower risk of developing cancers of the head and neck, including cancers of the mouth and throat, according to a review of previously published studies. Drinking 3-4 cups of coffee daily was linked to a 17 percent lower risk of head and neck cancer, while consuming one cup of tea was associated with a 9 percent lower risk, according to the findings published in the journal Cancer. Previous research has shown that bioactive compounds in coffee and tea, such as caffeine, have anti-inflammatory and antioxidant properties which contribute to lowering disease risk. A recent study also suggested that coffee, in moderation, could promote healthy longevity.

Card image cap
Sapience Therapeutics begins patient enrolment in phase 2 study of first-in-class ß-catenin antagonist, ST316 in colorectal cancer
Pharma Biz

Sapience Therapeutics announced that the first patient has been enrolled in its phase 2 dose expansion study evaluating ST316, the company’s first-in-class antagonist of ß-catenin.  Enrollment of the study’s phase 1 monotherapy dose escalation portion was completed in July 2024.

Card image cap
Breast Cancer Linked in Food Packaging; Scientists Raise Alarm
The Pioneer

Researchers have identified nearly 200 chemicals linked to breast cancer in food packaging materials and plastic tableware, with many capable of migrating into the human body. In a study published in ‘Frontiers in Toxicology’, they highlighted the presence of at least 189 potential breast carcinogens, including PFAS, bisphenols, and phthalates, in food contact materials (FCMs). Jane Muncke, study co-author, managing director and chief scientific officer at the Food Packaging Forum, a non-profit foundation based in Zurich, Switzerland said,  “There is strong evidence that 76 known or potential breast carcinogens from food contact materials recently purchased all over the world can be found in people.”

Card image cap
GSK’s experimental herpes vaccine fails to meet main goal in trial
Express Pharma

British drugmaker GSK said on Wednesday its experimental herpes simplex virus (HSV) vaccine candidate failed to meet the main goal of a mid-stage trial and would not be taken forward to a late-stage trial.

Card image cap
Dupixent data reinforce clinically meaningful benefit from pooled analysis of two COPD phase 3 studies
Pharma Biz

A pooled analysis from the BOREAS and NOTUS phase 3 studies showed that Dupixent reduced exacerbations and improved lung function compared to placebo in adults with uncontrolled chronic obstructive pulmonary disease (COPD) and evidence of type 2 inflammation (i.e., raised blood eosinophils).

Card image cap
Sanofi’s HERCULES phase 3 study of tolebrutinib to treat non-relapsing secondary progressive MS meets primary endpoint
Pharma Biz

Positive results from the HERCULES phase 3 study showed that tolebrutinib, Sanofi’s oral brain-penetrant BTK inhibitor, met the primary endpoint of improvement over placebo in delaying time to onset of confirmed disability progression (CDP) in people with non-relapsing secondary progressive MS (nrSPMS).

Card image cap
WHO alerts unregulated supply of Falsified (contaminated) Oxymorphone Hydrochloride 40mg
Express Pharma

This WHO Medical Product Alert refers to one batch of falsified Oxymorphone Hydrochloride 40mg. The falsified product was detected in the unregulated supply chain in Finland and reported to WHO in July 2024 by the Finnish Medicines Agency (FIMEA). Oxymorphone Hydrochloride is a semi-synthetic opioid used to treat moderate to severe pain. However, laboratory analysis of samples of the falsified product found that the tablets contained metonitazene instead.

Card image cap
Merck reports positive results from phase 2b/3 trial of clesrovimab, an investigational RSV preventative monoclonal antibody for infants
Pharma Biz

Merck announced positive topline results from its phase 2b/3 clinical trial (MK-1654-004) evaluating clesrovimab (MK-1654), the company’s investigational prophylactic monoclonal antibody designed to protect infants from respiratory syncytial virus (RSV) disease.

Doctors & Hospitals

Card image cap
Tata Memorial Hospital advises cancer patients to shun 'unproven remedies'
The Tribune

Cancer patients should not delay or stop their treatment by following unproven remedies, oncologists at Tata Memorial Hospital said after former India cricketer Navjot Singh Sidhu claimed at a presser that his wife Navjot Kaur defeated stage 4 cancer with dietary and lifestyle changes. In a statement posted on X, the Director of Tata Memorial Hospital, Dr C S Pramesh, said, "Parts of the video imply that starving the cancer by not eating dairy products and sugar, consuming haldi (turmeric) and neem helped cure her 'incurable' cancer." These comments have no high quality evidence to support them, the statement signed by 262 oncologists from the Tata Memorial Hospital, both past and present, said.

Card image cap
AIIMS Delhi Treats First Patient in GRASSROOT Trial for Treatment of Stroke Clots
Deccan Herald

Delhi AIIMS has launched the GRASSROOT (Gravity Stent-Retriever System for Reperfusion of Large Vessel Occlusion Stroke Trial) clinical trial to evaluate the safety and efficacy of an advanced brain stent for treatment of stroke clots particularly in Indian population. The study went live for enrolment on August 15 and the first patient was successfully treated on August 25. Subsequently, the patient was discharged from hospital, said Dr Shailesh Gaikwad, Professor and Head of Department of Neuroimaging and Intervential Neuroradiology at Neurosciences Centre, All India Institute of Medical Sciences (AIIMS), Delhi. The GRASSROOT trial is the first-ever study in India to test a novel next generation brain stent designed for Indian and Asian healthcare scenarios.

Card image cap
Yashoda Medicity introduces advanced radiation oncology technologies
Express Healthcare

Yashoda Medicity, a new healthcare facility by Yashoda Foundations in Indirapuram, has introduced three advanced technologies in its Radiation Oncology department, positioning itself as a leader in cancer treatment and care in the region. The adoption of these technologies makes Yashoda Medicity the only hospital in Southeast Asia equipped with such equipment.

Card image cap
Wockhardt Hospitals hosted Cyclothon Season 3 to promote heart health ahead of World Heart Day
Express Healthcare

Wockhardt Hospitals, Mira Road, organised the third season of its Cyclothon on September 1st, attracting more than 1,200 cyclists from across Mumbai, including major cycling groups. The event was held to raise awareness about heart health ahead of World Heart Day, which falls on September 29, 2024. Participants cycled through a 30 km and 15 km route across Uttan-Gorai Island, promoting fitness and heart health.

Card image cap
Rise in joint pain among young adults post-dengue recovery, say doctors
VIO

A growing number of Bengalureans, especially younger individuals, are reporting persistent joint pain long after recovering from dengue, causing concern among medical experts. Although they test negative for the virus, these patients experience severe joint discomfort, a symptom that was absent during their illness. Doctors are now investigating whether a mutation in the dengue virus may be responsible for this unexpected development, raising concerns about its impact on the city's youth.

Card image cap
HCMCT Manipal Hospital, Dwarka collaborates with Pfizer to launch CoE for adult vaccination
BioSpectrum

In a country where vaccination is often associated only with childhood immunisation and the need for adult vaccines is often overlooked, HCMCT Manipal Hospital and Pfizer India have collaborated to launch a dedicated Centre for adult vaccination at HCMCT Manipal Hospital, Dwarka, New Delhi, strengthening the delivery of adult vaccines.

Card image cap
TN Doctors Highlight Life-Saving Potential of Simple Urine Dipstick Test
VOH

A urine dipstick test, a simple and cost-effective diagnostic tool, can significantly prevent complications such as organ failure, heart attacks, and premature deaths, particularly among those with hypertension and diabetes, according to a newly released report by the Tamil Nadu Public Health Department. Doctors analyzed data from 5.7 million people across Tamil Nadu who took the test between July 2023 and May 2024 as part of a state ‘urine dipstick testing program’ for the early detection of chronic kidney disease (CKD). The test was administered at all primary health centers and health sub-centers for individuals with diabetes and hypertension. The urine dipstick test, recommended during routine check-ups or when urinary tract infection, kidney disease, or diabetes is suspected, involves dipping a plastic stick with chemically treated pads into a urine sample. The results revealed that 13,082 patients had high levels of albumin, an important indicator of kidney damage.

Card image cap
Dengue can seriously affect your brain, nervous system: Doctors
The Tribune

Although dengue is known to cause mild flu-like symptoms, the mosquito-borne viral illness has profound neurological implications that are often overlooked, said experts on Tuesday. Amid the monsoon in India, dengue cases have spiralled in various parts of the country, including Karnataka, Kerala, Telangana, Andhra Pradesh, Odisha, Delhi and Maharashtra. According to the latest data from the Municipal Corporation of Delhi (MCD), there have been 246 dengue cases in the national capital till June 30 this year. During the same period in 2023, Delhi saw only 122 cases, 143 cases in 2022, 36 cases in 2021, and 20 cases in 2020.

Card image cap
Health experts stress the need for adult vaccination during World Immunisation Week
The New Indian Express

From polio to the coronavirus, vaccines play a pivotal role in protecting human health against a range of perilous diseases. As researchers strive to comprehend viruses and innovate new vaccines, it’s imperative to emphasise the significance of immunisation. Hence, World Immunisation Week is observed annually from April 24 to 30. During this week, let’s explore the significance of both traditional and emerging vaccines that are essential for everyone.

Drug Discovery

Card image cap
New eye drop treatment offers hope for dry AMD patients
Medical News

Age-related macular degeneration (AMD) is the leading cause of vision loss in individuals over 65, characterized by abnormal changes in the macular, resulting in reduced vision and distorted objects. Dry AMD accounts for 90 percent of all AMD cases, with relatively mild vision impairment; however, approximately 30 percent progress to the severe vision loss associated with wet AMD within 10 years. The only FDA-approved treatments for dry AMD as of 2023 are two injectable drugs, which are limited by concerns over complications from intravitreal injections and modest efficacy in restoring vision.

Card image cap
New RSV drug for babies is over 90 percent effective at preventing hospitalization
Live Science

A new RSV drug designed to protect young children was 93 percent effective at preventing hospitalization for the viral disease, a new study reports. Furthermore, the drug was 89 percent effective at preventing all types of doctor visits for RSV, which is short for "respiratory syncytial virus."

Card image cap
Researchers in Japan discover new antidiabetic compound
News Medical

Kumamoto University scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation. Type 2 diabetes, a condition affecting millions worldwide, is often accompanied by complications like fatty liver and insulin resistance, which challenge current treatment methods.

Card image cap
Scientists identify a form of vitamin B6 as a means of engaging tumor-reactive immune cells
Medical Xpress

Effective immunity hinges on the ability to sense infection and cellular transformation. In humans, there is a specialized molecule on the surface of cells termed MR1. MR1 allows sensing of certain small molecule metabolites derived from cellular and microbial sources; however, the breadth of metabolite sensing is unclear.

Card image cap
Diabetes drug Metformin might help fight lung cancer
US News

Already the go-to drug of choice for millions with type 2 diabetes, metformin might also fight lung cancer if those patients have it as well, new research shows. Metformin appears to help boost the benefits of immunotherapy drugs used to fight lung tumors, according to a team led by Dr. Sai Yendamuri. He directs thoracic surgery at Roswell Park Comprehensive Cancer Center in Buffalo, N.Y.

Card image cap
Popular diabetes and obesity drugs also protect kidneys, study shows
Eurek Alert

The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without diabetes.1 Findings were published today in The Lancet Diabetes & Endocrinology. Originally developed to treat diabetes, GLP-1 receptor agonists mimic the action of a hormone called glucagon-like peptide 1, which stimulates insulin production and lowers blood sugar levels. More recently, they have emerged as effective treatments for obesity - slowing digestion, increasing feelings of fullness, and reducing hunger.

Card image cap
Scientists find why tamoxifen works better for some people
Science Daily

A new study has shown that variation in the microbiota of the human gut impacts the pharmacokinetics of tamoxifen and thus the effectiveness of the drug. The finding, published in the journal mBio of the American Society for Microbiology, suggests that in the future, doctors may use a simple test on a patient's stool to check for certain bacteria in the gut that might help predict whether tamoxifen will work for them.

Card image cap
Weight-loss drug Tirzepatide reduces heart failure deaths
UVA Health

Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with heart failure, preserved heart pump function and obesity, new research from UVA Health reveals. The drug, from pharmaceutical company Eli Lilly and Co., was tested in the SUMMIT clinical trial at 146 sites in the United States and abroad. A total of 731 patients with diastolic heart failure and a body mass index (BMI) of 30 or above were randomized to receive injections of either tirzepatide or a harmless placebo. The researchers then followed the patients for a median period of two years.

Card image cap
New drug targets for Alzheimer's identified from cerebrospinal fluid
Neuro Science

A multitude of genes have been linked to the development of Alzheimer's disease. Specifically how those genes might influence the progression of neurodegeneration remains something of a black box though, in part because of the challenges of examining in molecular detail the brain of a living patient. Using cerebrospinal fluid (CSF) collected from living patients, a team of researchers at Washington University School of Medicine in St. Louis has for the first time linked disease-related proteins and genes to identify specific cellular pathways responsible for Alzheimer's genesis and progression. Because these proteins were gathered from CSF, they are a good proxy for activity in the brain, and several of them may be potential targets for therapies.

Becares-Weekly

Card image cap
Corbevax vaccine for kids: Everything you need to know about this Covid jab
Live Mint

Biological E Limited's Corbevax is being administered to children in the age group 12-14 in India. This age group got the Indian government's nod to be receive vaccine against the novel coronavirus from 16 March, Wednesday. These children have to register for getting the vaccine on the CoWIN portal. India's third indigenous anti-Covid vaccine has been manufactured by Hyderabad-based Biological E Limited. Biological E has supplied 5 crore doses of Corbevax to the Centre, which has then distributed the same to states.

Card image cap
Corbevax vaccine for 5-12 years: Confident of getting EUA, Biological E says
Live Mint

Biological E seems confident regarding getting emergency use authorisation for use of its COVID vaccine Corbevax among children in the age group of 5-12 years. Currently, the vaccine is inoculated among children in the age group of 12 to 14 years The Hyderabad-based company Is qualified to produce around 1 billion dosages of Corbevax annually and it is geared up to meet any increase in demand. Currently, the company has produced 30 crore vaccines as part of its commitment made to the Government of India, with 5 crore dosages already supplied.

Card image cap
Ready with 30 crore doses, can scale up production if needed: Corbevax makers
The Indian Express

Biotech firm Biological E. Limited is geared to facilitate the first phase of the vaccination drive for the 12-15 age group and is ready with 30 crore doses of which five crore has been rolled out to 17 different sites in the country, said a top official of the firm. "This is the most affordable COVID-19 vaccine for the Government of India which is providing free vaccination to all eligible citizens. The pricing of CORBEVAX in the private market will be Rs 800 (and inclusive of all taxes and vaccine administration charges will cost Rs 990) The vaccine is being sold at Rs 145 per dose to the government," Mahima Datla, managing director of Biological E. Limited said at a virtual media interaction on Wednesday. "We have an annual production capacity upto one billion vaccines," Datla said. The firm collaborated with the Texas Children's Hospital and the Baylor College to develop Corbevax vaccine. Dynavax, Inc from USA supported Corbevax development by providing the adjuvant and THSTI Delhi conducted key immunogenicity testing as part of a comprehensive clinical trial development plan.

Card image cap
Covid-19: 12-14 vaccination drive off to slow start in Delhi; pick-up likely after Holi
The Times of India

Only about 3,800 children aged between 12 and 14 were vaccinated against Covid-19 in the city on Wednesday, the first day of vaccination for this cohort in the country. All the children were administered Corbevax, India's first indigenously developed protein subunit vaccine against Covid-19, made by Biological E. Each dose in the private market will cost Rs 800 per dose, excluding GST, and around Rs 990, including taxes and administration charges. For the government, the price will be Rs 145. There are nearly 6.2 lakh children in this age group in Delhi who are eligible for the vaccine. Hospital officials said the first day saw a lukewarm response; footfall is expected to pick up after Holi.

Medical Specialties

Card image cap
Delhi doctors treat 1.5-month-old baby with a hole in the heart
Bhaskar Live

The baby was brought to Fortis Escorts Heart Institute, Okhla, in a serious condition with breathing difficulties, sepsis-like symptoms, heart failure signs, elevated heart rate, excessive perspiration, inability to feed, liver enlargement, and failure to gain weight. An echocardiogram revealed that the baby suffered from a hole in the heart, also known as patent ductus arteriosus (PDA) — a condition where an extra blood vessel is found in babies before birth and just after birth.

Card image cap
In rare recovery, Kerala boy survives amoebic meningoencephalitis which has 97 percent mortality rate
Deccan Herald

Amidst concerns over the outbreak of deadly virus infections like Nipah in Kerala, the state on Monday reported a rare case of recovery from amoebic meningoencephalitis, which has a 97 percent mortality rate. State Health Minister Veena George's office on Monday confirmed that it was a rare occurrence, which has a mortality rate of 97 percent and it is believed that only 11 persons in the world so far recovered from the infection. Earlier detection of the infection helped in speedy recovery of the boy. The minister also praise the efforts of the medical team that treated the boy.

Card image cap
Scientists create first-ever 'Chimeroids' using cells from multiple people
Live Science

For the first time, scientists have grown 3D brain models using cells from multiple people. The new hybrid creations, which researchers have dubbed "chimeroids," are a variation of brain organoids — tiny 3D models made of tissue that mimic the structure and function of a full-size brain. These models are more accurate to human biology than 2D cellular models or animals like lab mice. Because of this, scientists hope that the models will accelerate drug research and development.

Card image cap
‘Placebo’ or ‘sham’ surgery is not a cruel trick – it can be very effective
The Conversation

Ten years ago, a scan showed that I had torn the meniscus in my knee. The pain was bad and I was limping a lot of the time. My doctor recommended arthroscopic knee surgery to fix it. Being scared of scalpels, I asked whether there were other options. He said I could try physiotherapy, but that it was unlikely to work. I tried the physio and did the recommended exercises diligently, and my knee pain and function returned to almost normal. I even ran my first (and only) marathon a year later.

Card image cap
AI’s healthcare solutions: From diagnosis to supplying meds
The Times of India

A small farmer from a remote village walks into the nearest town’s health clinic. He breathes into a tube connected to a Vionix analyser. This device compares the farmer’s breath with hundreds of millions of other samples from around the world. An AI model, running on the cloud, identifies patterns of disease manifestations in the spectral signatures of the breath sample and instantly provides results on the farmer’s smartphone.

Card image cap
Man who received first pig kidney transplant dies
BCC

The first man to receive a genetically modified pig kidney transplant has died two months after the operation, the hospital which carried out the procedure has said. Richard "Rick" Slayman, 62, was suffering with end-stage kidney disease before undergoing the operation in March. Massachusetts General Hospital (MGH) said on Sunday there was no indication his death was a result of the transplant.

Card image cap
Baby born deaf can hear after breakthrough gene therapy
Pharma Biz

A girl born deaf can now hear unaided after participating in a world-first trial. The CHORD study is for children born with hearing loss due to a genetic condition called auditory neuropathy. Auditory neuropathy is a condition where the ear can detect sound normally, but has a problem sending signals to the brain.

Card image cap
Researchers give more insight into hip osteoarthritis among older adults with spinal deformity
ANI News

A study found that one-third of patients receiving surgery for adult spinal deformity (ASD) also have severe hip osteoarthritis (OA), which can lead to poor spinal alignment and physical functionality. Findings of the study published in The Journal of Bone & Joint Surgery.

Card image cap
A new therapeutic target for traumatic brain injury
PR Newswire

For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, but they come with an amplified risk for developing dementia in the future. The glaring absence of treatments for such a widespread condition drove a team of scientists at Gladstone Institutes to uncover, on a molecular level, how traumatic brain injuries trigger neurodegeneration—and just as importantly, how to target that process to prevent long-term damage.

Vaccine Launch & Research

Card image cap
Immunocompromised may not produce enough protective antibodies against RSV after vaccination, says new study
Johns Hopkins Medicine

Johns Hopkins Medicine researchers have shown that people 60 years or older with weakened immunity—primarily organ transplant recipients who take immunosuppressive medications to reduce the risk of rejection and others with immune system disorders—do not respond as strongly to vaccines against the respiratory syncytial virus (RSV) as people in the same age group with normal immune function.

Card image cap
Serum to make chikungunya vaccine in India
Financial Express

Serum Institute of India (SII) has entered into an exclusive licence agreement with French speciality vaccine company Valneva SE to manufacture and sell Valneva’s chikungunya vaccine in India and the rest of Asia. Valneva’s chikungunya vaccine is the world’s first and only licensed vaccine. It is currently approved in the US, Europe, and Canada for adults.  Regulatory reviews are underway to expand it to children up to 12 years.

Card image cap
Interim results of malaria vaccine Phase 2b trial show 'promising efficacy'
The Week

A new malaria vaccine appears to be "safe and highly immunogenic", with "promising efficacy", according to interim results of the phase 2b clinical trial conducted in African children. The vaccine candidate, named 'RH5.1/Matrix-M', is a blood-stage type, targeting the malaria-causing parasite when it is present in the blood -- the stage of the parasite's life cycle when symptoms begin to show in the affected person. The trial results were published in "The Lancet Infectious Diseases" journal. Malaria is caused by Plasmodium parasites, spread to humans through the bite of an infected female Anopheles mosquito. Symptoms usually appear in the 10-15 days following the bite, with mild symptoms being fever, chills and headache, while the severe ones can include fatigue, confusion, seizures, and difficulty in breathing.

Card image cap
International study shows updated hepatitis b vaccine more effective for people with HIV
Medical Xpress

A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn't respond to prior vaccination, according to the results of an international study led by a Weill Cornell Medicine investigator. The study, reported Dec. 1 in JAMA, showed that hepatitis B vaccine with a cytosine phosphoguanine adjuvant, known as HepB-CpG, (trade name Heplisav-B) induced protective levels of antibodies in up to 99.4 percent of the subjects who received it. Such protection was seen in only 80.6 percent of subjects who received hepatitis B vaccine with an aluminum hydroxide adjuvant, known as HepB-alum, (trade name Engerix-B).

Card image cap
Broadly effective vaccine design offers new hope in the fight against hepatitis C
Medical Xpress

The development of an effective vaccine against the hepatitis C virus (HCV) has posed a significant challenge for decades due to the high genetic diversity of the virus. A research team has now achieved promising results. Using epitope-focused immunogens, they were able to induce broadly neutralizing antibodies (bnAbs) in laboratory models for the first time.

Card image cap
Possible colon cancer vaccine target uncovered in bacteria
Medical Express

Higher rates of certain cancers in countries, such as the UK, may be linked to two particular strains of bacteria. Targeting these with treatments or vaccines could help reduce the risk of colorectal, bladder, and prostate cancers. Researchers from the Wellcome Sanger Institute, the University of Helsinki, and collaborators investigated the differences in cancer incidence for colorectal, bladder and prostate cancers, and compared these to global data tracking Escherichia coli (E. coli) strains. Specifically, they looked at the two dominant E. coli strains that produce a substance that has been previously identified as a risk factor for colorectal cancer.

Card image cap
AICC RCOG recommends mandatory vaccination for cervical cancer prevention
The Week

The All India Coordinating Committee of Royal College of Obstetricians & Gynecologists (AICC RCOG) has recommended mandatory vaccination of adolescents and young adults to prevent cervical cancer, a statement said on Monday. The RCOG panel supports HPV vaccination and advocates for its accessibility to all eligible individuals, as this represents a crucial step toward the prevention and control of HPV diseases in India, the statement said.

Card image cap
New malaria vaccine shows high protection in clinical trial
Medical Xpress

Researchers at Leiden University Medical Center and Radboud University Medical Center in the Netherlands have demonstrated promising safety and efficacy of a late-liver-stage attenuated malaria parasite vaccine in a small clinical trial. The study found that immunization with a genetically modified Plasmodium falciparum parasite, known as GA2, induced a favorable immune response and provided protective efficacy against malaria infection.

Card image cap
WHO adds new mpox vaccine to Emergency Use Listing
Financial Express

The World Health Organization (WHO) on Wednesday announced that it has granted Emergency Use Listing (EUL) for the LC16m8 mpox vaccine. According to the global health agency’s statement, this is the second mpox vaccine to be supported by WHO following the Director-General’s declaration of an mpox public health emergency of international concern (PHEIC) on 14 August 2024.

Disease Studies

Card image cap
Stigma around TB kills more women than men: Reliance Foundation Hospital study
ANI News

Reliance Foundation Hospital recently released a study on tuberculosis in women. As per the study, in 2022, an estimated 10.6 million people fell ill with TB worldwide, including 5.8 million men, 3.5 million women and 1.3 million children.

Card image cap
New genetic mutation found to suppress cancer growth
Medical Xpress

UT Southwestern Medical Center researchers have identified a genetic mutation that slows the growth of melanoma and potentially other cancers by harnessing the power of the immune system. Their findings, published in the Journal of Experimental Medicine, could lead to new treatments that improve outcomes from existing cancer immunotherapies.

Card image cap
Digital consultations not sufficient for treatment of tonsillitis, says study
The Tribune

Even as digital healthcare consultations are becoming more common, a study showed it may not be enough for a safe assessment of tonsillitis. Tonsillitis is a painful infection of the tonsils—two lymph node-rich glands in the back of the throat. Symptoms of tonsillitis include swollen tonsils, sore throat, and difficulty swallowing. The study showed that digital assessment may not be reliable, thus increasing the risk of over- or undertreatment of a sore throat.

Card image cap
New clinical practice guideline on process for diagnosing Alzheimer’s disease or a related form of cognitive impairment or dementia
Pharma Biz

An expert workgroup representing primary and specialty care has developed new guidelines for comprehensive evaluation of patients who may have cognitive impairment or dementia due to Alzheimer’s disease or a related disease. Current guidelines for a comprehensive evaluation process are more than 20 years old.

Card image cap
Superbugs Push Indian Families into Debt : ICMR Study Reveals
VOH

Antibiotic resistance in India has reached alarming levels, driving many families into debt due to the escalating costs of treatment, a study by the Indian Council of Medical Research (ICMR) has revealed. The study, published in BMJ Open, highlights how the treatment of antibiotic-resistant bacterial infections in private hospitals can cost up to 10.6 percent more than treating drug-susceptible infections.

Card image cap
Russian technology strengthens Latin America’s battle against mosquito-borne diseases
Financial Express

In a groundbreaking collaboration, Bolivia has turned to Russian technology to tackle one of the most pressing public health challenges in tropical regions: mosquito-borne diseases. For the first time, the Bolivian Nuclear Energy Agency (ABEN), together with the National Institute of Health Laboratories (INLASA) and the National Public Health Research Institute (INSPI), has utilized Russian gamma irradiation technology at Bolivia’s Multipurpose Irradiation Center (MIC). This initiative is focused on sterilizing yellow fever mosquitoes, a key step in controlling the spread of dangerous diseases like dengue, malaria, and Zika virus.

Card image cap
Health of blood vessels can reveal health of brain, study finds
News Meter

Brain imaging of 70-year-olds has shown that factors risking the health of blood vessels, such as inflammation and high glucose levels, are related to an older-looking brain, whereas healthy lifestyles to a younger one. As the population around the world ages, dementia cases are projected to rise. However, researchers from Karolinska Institutet, Sweden, said that the speed at which one's brain ages is affected by various risk and health factors. "Despite the recent introduction of new Alzheimer's drugs, they will not work for everyone with dementia. So, we want to study what can boost the brain's resilience against pathological ageing processes," Anna Marseglia, a researcher at Karolinska Institutet and lead author of the study published in the Alzheimer's & Dementia: The Journal of the Alzheimer's Association, said.

Card image cap
Scientists develop scan that unravels secrets of lung function
The Tribune

A team of scientists has developed a new method of scanning lungs that is able to show the effects of treatment on lung function in real time, enabling them to see the functioning of transplanted lungs. The scan method enabled the team, led by researchers at Newcastle University in the UK, to see how air moves in and out of the lungs as people take a breath in patients with asthma, chronic obstructive pulmonary disease (COPD), and patients who have received a lung transplant.

Card image cap
Study finds transfusing more blood to anemic patients after heart attack could save lives
The Tribune

According to a study conducted by Rutgers Health, giving more blood to anemic patients after a heart attack could save their lives. The study confirms research completed in 2023, which revealed that anemic patients who received less blood had a higher mortality rate or more frequent heart attacks. Jeffrey L. Carson, provost and Distinguished Professor of medicine at Rutgers Robert Wood Johnson Medical School, led both studies.

Disclaimer: This news page has curated abstracts of daily healthcare news stories from various daily news outlets. To view the complete story, click on the link (provided with each news). Biological E Limited in collaboration with TodaySource has not verified these news stories and are not liable for the authenticity of the news.
If you choose to provide us with your email address or any other personally identifiable information, we will use it only to send you our newsletter or respond to your query.