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New Medicine

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Delhi doctors treat 1.5-month-old baby with a hole in the heart
Bhaskar Live

The baby was brought to Fortis Escorts Heart Institute, Okhla, in a serious condition with breathing difficulties, sepsis-like symptoms, heart failure signs, elevated heart rate, excessive perspiration, inability to feed, liver enlargement, and failure to gain weight. An echocardiogram revealed that the baby suffered from a hole in the heart, also known as patent ductus arteriosus (PDA) — a condition where an extra blood vessel is found in babies before birth and just after birth.

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In rare recovery, Kerala boy survives amoebic meningoencephalitis which has 97 percent mortality rate
Deccan Herald

Amidst concerns over the outbreak of deadly virus infections like Nipah in Kerala, the state on Monday reported a rare case of recovery from amoebic meningoencephalitis, which has a 97 percent mortality rate. State Health Minister Veena George's office on Monday confirmed that it was a rare occurrence, which has a mortality rate of 97 percent and it is believed that only 11 persons in the world so far recovered from the infection. Earlier detection of the infection helped in speedy recovery of the boy. The minister also praise the efforts of the medical team that treated the boy.

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Scientists create first-ever 'Chimeroids' using cells from multiple people
Live Science

For the first time, scientists have grown 3D brain models using cells from multiple people. The new hybrid creations, which researchers have dubbed "chimeroids," are a variation of brain organoids — tiny 3D models made of tissue that mimic the structure and function of a full-size brain. These models are more accurate to human biology than 2D cellular models or animals like lab mice. Because of this, scientists hope that the models will accelerate drug research and development.

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‘Placebo’ or ‘sham’ surgery is not a cruel trick – it can be very effective
The Conversation

Ten years ago, a scan showed that I had torn the meniscus in my knee. The pain was bad and I was limping a lot of the time. My doctor recommended arthroscopic knee surgery to fix it. Being scared of scalpels, I asked whether there were other options. He said I could try physiotherapy, but that it was unlikely to work. I tried the physio and did the recommended exercises diligently, and my knee pain and function returned to almost normal. I even ran my first (and only) marathon a year later.

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AI’s healthcare solutions: From diagnosis to supplying meds
The Times of India

A small farmer from a remote village walks into the nearest town’s health clinic. He breathes into a tube connected to a Vionix analyser. This device compares the farmer’s breath with hundreds of millions of other samples from around the world. An AI model, running on the cloud, identifies patterns of disease manifestations in the spectral signatures of the breath sample and instantly provides results on the farmer’s smartphone.

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Man who received first pig kidney transplant dies
BCC

The first man to receive a genetically modified pig kidney transplant has died two months after the operation, the hospital which carried out the procedure has said. Richard "Rick" Slayman, 62, was suffering with end-stage kidney disease before undergoing the operation in March. Massachusetts General Hospital (MGH) said on Sunday there was no indication his death was a result of the transplant.

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Baby born deaf can hear after breakthrough gene therapy
Pharma Biz

A girl born deaf can now hear unaided after participating in a world-first trial. The CHORD study is for children born with hearing loss due to a genetic condition called auditory neuropathy. Auditory neuropathy is a condition where the ear can detect sound normally, but has a problem sending signals to the brain.

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Researchers give more insight into hip osteoarthritis among older adults with spinal deformity
ANI News

A study found that one-third of patients receiving surgery for adult spinal deformity (ASD) also have severe hip osteoarthritis (OA), which can lead to poor spinal alignment and physical functionality. Findings of the study published in The Journal of Bone & Joint Surgery.

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A new therapeutic target for traumatic brain injury
PR Newswire

For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, but they come with an amplified risk for developing dementia in the future. The glaring absence of treatments for such a widespread condition drove a team of scientists at Gladstone Institutes to uncover, on a molecular level, how traumatic brain injuries trigger neurodegeneration—and just as importantly, how to target that process to prevent long-term damage.

Global coverage

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Sanofi begins phase 3 program for pneumococcal conjugate vaccine (PCV21); expands agreement with SK bioscience
Pharma Biz

Sanofi and SK bioscience have entered into a new chapter of their collaboration in pneumococcal vaccines with an expanded agreement to develop, license and commercialize next-generation PCVs for both pediatric and adult populations, reaffirming their commitment to fighting pneumococcal disease.

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Drinking tea, coffee linked to lower risk of head and neck cancer: Study
The Tribune

Drinking tea or coffee is associated with a lower risk of developing cancers of the head and neck, including cancers of the mouth and throat, according to a review of previously published studies. Drinking 3-4 cups of coffee daily was linked to a 17 percent lower risk of head and neck cancer, while consuming one cup of tea was associated with a 9 percent lower risk, according to the findings published in the journal Cancer. Previous research has shown that bioactive compounds in coffee and tea, such as caffeine, have anti-inflammatory and antioxidant properties which contribute to lowering disease risk. A recent study also suggested that coffee, in moderation, could promote healthy longevity.

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Sapience Therapeutics begins patient enrolment in phase 2 study of first-in-class ß-catenin antagonist, ST316 in colorectal cancer
Pharma Biz

Sapience Therapeutics announced that the first patient has been enrolled in its phase 2 dose expansion study evaluating ST316, the company’s first-in-class antagonist of ß-catenin.  Enrollment of the study’s phase 1 monotherapy dose escalation portion was completed in July 2024.

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Breast Cancer Linked in Food Packaging; Scientists Raise Alarm
The Pioneer

Researchers have identified nearly 200 chemicals linked to breast cancer in food packaging materials and plastic tableware, with many capable of migrating into the human body. In a study published in ‘Frontiers in Toxicology’, they highlighted the presence of at least 189 potential breast carcinogens, including PFAS, bisphenols, and phthalates, in food contact materials (FCMs). Jane Muncke, study co-author, managing director and chief scientific officer at the Food Packaging Forum, a non-profit foundation based in Zurich, Switzerland said,  “There is strong evidence that 76 known or potential breast carcinogens from food contact materials recently purchased all over the world can be found in people.”

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GSK’s experimental herpes vaccine fails to meet main goal in trial
Express Pharma

British drugmaker GSK said on Wednesday its experimental herpes simplex virus (HSV) vaccine candidate failed to meet the main goal of a mid-stage trial and would not be taken forward to a late-stage trial.

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Dupixent data reinforce clinically meaningful benefit from pooled analysis of two COPD phase 3 studies
Pharma Biz

A pooled analysis from the BOREAS and NOTUS phase 3 studies showed that Dupixent reduced exacerbations and improved lung function compared to placebo in adults with uncontrolled chronic obstructive pulmonary disease (COPD) and evidence of type 2 inflammation (i.e., raised blood eosinophils).

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Sanofi’s HERCULES phase 3 study of tolebrutinib to treat non-relapsing secondary progressive MS meets primary endpoint
Pharma Biz

Positive results from the HERCULES phase 3 study showed that tolebrutinib, Sanofi’s oral brain-penetrant BTK inhibitor, met the primary endpoint of improvement over placebo in delaying time to onset of confirmed disability progression (CDP) in people with non-relapsing secondary progressive MS (nrSPMS).

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WHO alerts unregulated supply of Falsified (contaminated) Oxymorphone Hydrochloride 40mg
Express Pharma

This WHO Medical Product Alert refers to one batch of falsified Oxymorphone Hydrochloride 40mg. The falsified product was detected in the unregulated supply chain in Finland and reported to WHO in July 2024 by the Finnish Medicines Agency (FIMEA). Oxymorphone Hydrochloride is a semi-synthetic opioid used to treat moderate to severe pain. However, laboratory analysis of samples of the falsified product found that the tablets contained metonitazene instead.

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Merck reports positive results from phase 2b/3 trial of clesrovimab, an investigational RSV preventative monoclonal antibody for infants
Pharma Biz

Merck announced positive topline results from its phase 2b/3 clinical trial (MK-1654-004) evaluating clesrovimab (MK-1654), the company’s investigational prophylactic monoclonal antibody designed to protect infants from respiratory syncytial virus (RSV) disease.

Medical Specialties

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Delhi doctors treat 1.5-month-old baby with a hole in the heart
Bhaskar Live

The baby was brought to Fortis Escorts Heart Institute, Okhla, in a serious condition with breathing difficulties, sepsis-like symptoms, heart failure signs, elevated heart rate, excessive perspiration, inability to feed, liver enlargement, and failure to gain weight. An echocardiogram revealed that the baby suffered from a hole in the heart, also known as patent ductus arteriosus (PDA) — a condition where an extra blood vessel is found in babies before birth and just after birth.

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In rare recovery, Kerala boy survives amoebic meningoencephalitis which has 97 percent mortality rate
Deccan Herald

Amidst concerns over the outbreak of deadly virus infections like Nipah in Kerala, the state on Monday reported a rare case of recovery from amoebic meningoencephalitis, which has a 97 percent mortality rate. State Health Minister Veena George's office on Monday confirmed that it was a rare occurrence, which has a mortality rate of 97 percent and it is believed that only 11 persons in the world so far recovered from the infection. Earlier detection of the infection helped in speedy recovery of the boy. The minister also praise the efforts of the medical team that treated the boy.

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Scientists create first-ever 'Chimeroids' using cells from multiple people
Live Science

For the first time, scientists have grown 3D brain models using cells from multiple people. The new hybrid creations, which researchers have dubbed "chimeroids," are a variation of brain organoids — tiny 3D models made of tissue that mimic the structure and function of a full-size brain. These models are more accurate to human biology than 2D cellular models or animals like lab mice. Because of this, scientists hope that the models will accelerate drug research and development.

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‘Placebo’ or ‘sham’ surgery is not a cruel trick – it can be very effective
The Conversation

Ten years ago, a scan showed that I had torn the meniscus in my knee. The pain was bad and I was limping a lot of the time. My doctor recommended arthroscopic knee surgery to fix it. Being scared of scalpels, I asked whether there were other options. He said I could try physiotherapy, but that it was unlikely to work. I tried the physio and did the recommended exercises diligently, and my knee pain and function returned to almost normal. I even ran my first (and only) marathon a year later.

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AI’s healthcare solutions: From diagnosis to supplying meds
The Times of India

A small farmer from a remote village walks into the nearest town’s health clinic. He breathes into a tube connected to a Vionix analyser. This device compares the farmer’s breath with hundreds of millions of other samples from around the world. An AI model, running on the cloud, identifies patterns of disease manifestations in the spectral signatures of the breath sample and instantly provides results on the farmer’s smartphone.

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Man who received first pig kidney transplant dies
BCC

The first man to receive a genetically modified pig kidney transplant has died two months after the operation, the hospital which carried out the procedure has said. Richard "Rick" Slayman, 62, was suffering with end-stage kidney disease before undergoing the operation in March. Massachusetts General Hospital (MGH) said on Sunday there was no indication his death was a result of the transplant.

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Baby born deaf can hear after breakthrough gene therapy
Pharma Biz

A girl born deaf can now hear unaided after participating in a world-first trial. The CHORD study is for children born with hearing loss due to a genetic condition called auditory neuropathy. Auditory neuropathy is a condition where the ear can detect sound normally, but has a problem sending signals to the brain.

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Researchers give more insight into hip osteoarthritis among older adults with spinal deformity
ANI News

A study found that one-third of patients receiving surgery for adult spinal deformity (ASD) also have severe hip osteoarthritis (OA), which can lead to poor spinal alignment and physical functionality. Findings of the study published in The Journal of Bone & Joint Surgery.

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A new therapeutic target for traumatic brain injury
PR Newswire

For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, but they come with an amplified risk for developing dementia in the future. The glaring absence of treatments for such a widespread condition drove a team of scientists at Gladstone Institutes to uncover, on a molecular level, how traumatic brain injuries trigger neurodegeneration—and just as importantly, how to target that process to prevent long-term damage.

Vaccine Launch & Research

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Scientists find clues on why COVID vaccine causes chronic health problems in some
Yahoo

For a majority of people, the COVID vaccine doesn’t cause adverse health effects — but a small percentage experience chronic symptoms that can last for months or even years. Yale researchers recently made some discoveries about why certain people experience this condition, which they have dubbed "post-vaccination syndrome" (PVS). In early findings, the team recognized "potential immunological patterns" that are unique to people with PVS. The hope is that this discovery will help to enable future treatments and therapies for those who are affected.

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Pancreatic cancer RNA vaccine shows durable T cell immunity
Medical Xpress

Memorial Sloan Kettering Cancer Center researchers have found RNA neoantigen vaccines that generate long-lived, functional CD8+ T cells in patients with pancreatic ductal adenocarcinoma (PDAC), potentially delaying disease recurrence. PDAC is a lethal cancer with limited treatment options and a low mutational burden. T cells defend the body by destroying harmful outside pathogens and mutated body cells, such as cancer.

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RSV vaccine sees drop in hospitalisation of older people
Nursing In Practice

A new study has found a major drop in respiratory syncytial virus (RSV) related hospitalisations following vaccination among eligible age groups in Scotland. The study, from Public Health Scotland (PHS) and the University of Strathclyde, showed a 62 percent reduction in RSV-related hospitalisations among those who received the vaccine and concludes the vaccine is effective in reducing such hospitalisations in older adults.

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ICMR testing BCG vaccine for tuberculosis
The Tribune

India is looking at several potential vaccine candidates for deployment in the tuberculosis elimination programme with the Indian Council for Medical Research testing the BCG vaccine for TB control. ICMR chief and secretary health research Rajiv Bahl said the BCG vaccine, currently administered to children, was being tested in adults vulnerable to TB. The Bacillus Calmette-Guérin (BCG) vaccine is given to children at risk of tuberculosis (TB). It's a common vaccine in countries where TB is prevalent. India houses nearly one fourth of the global TB-affected people and has a target of elimination of the disease by 2025.

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HPV vaccine to be rolled out in a few months time: Top health ministry official
The Indian Express

India plans to roll out the HPV vaccine in the national immunization programme for school girls to protect them from cervical cancer “in a few months” time, top health ministry officials said Tuesday. “The HPV vaccine will be rolled out in a few months but we will have to wait for the TB vaccine,” said Union Health Secretary Punya Salila Srivastava at a press conference held by Union Health Minister J P Nadda. Without giving any more details, she said, the ministry is strategizing the way forward. Cervical cancer, which is the second most common cancer in India, is a preventable and curable disease if detected early and treated adequately. Cervical cancer is a significant public health challenge in India, accounting for 77,348 cervical cancer deaths in women, annually.

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COVID-19 vaccines fail to alter neuro symptoms of Long COVID
The Hindu

While COVID-19 vaccination decreases the severity of COVID-19 disease and the rate of hospitalisation and death, a study published recently has found that vaccination prior to SARS-CoV-2 infection does not necessarily reduce the neurological manifestations and burden of Long COVID. This includes patients who had a severe infection that necessitated hospitalisation and those with a mild infection who did not require hospitalisation. Common neurological symptoms of Long COVID include brain fog, numbness and tingling, headache, dizziness, problems with smell and taste, and intense fatigue.

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Immunocompromised may not produce enough protective antibodies against RSV after vaccination, says new study
Johns Hopkins Medicine

Johns Hopkins Medicine researchers have shown that people 60 years or older with weakened immunity—primarily organ transplant recipients who take immunosuppressive medications to reduce the risk of rejection and others with immune system disorders—do not respond as strongly to vaccines against the respiratory syncytial virus (RSV) as people in the same age group with normal immune function.

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Serum to make chikungunya vaccine in India
Financial Express

Serum Institute of India (SII) has entered into an exclusive licence agreement with French speciality vaccine company Valneva SE to manufacture and sell Valneva’s chikungunya vaccine in India and the rest of Asia. Valneva’s chikungunya vaccine is the world’s first and only licensed vaccine. It is currently approved in the US, Europe, and Canada for adults.  Regulatory reviews are underway to expand it to children up to 12 years.

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Interim results of malaria vaccine Phase 2b trial show 'promising efficacy'
The Week

A new malaria vaccine appears to be "safe and highly immunogenic", with "promising efficacy", according to interim results of the phase 2b clinical trial conducted in African children. The vaccine candidate, named 'RH5.1/Matrix-M', is a blood-stage type, targeting the malaria-causing parasite when it is present in the blood -- the stage of the parasite's life cycle when symptoms begin to show in the affected person. The trial results were published in "The Lancet Infectious Diseases" journal. Malaria is caused by Plasmodium parasites, spread to humans through the bite of an infected female Anopheles mosquito. Symptoms usually appear in the 10-15 days following the bite, with mild symptoms being fever, chills and headache, while the severe ones can include fatigue, confusion, seizures, and difficulty in breathing.

Disease Studies

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Test identifies prior infection by Zika virus and all four dengue virus serotypes
Medical Xpress

Brazilian researchers have developed a simple test that almost instantly tells whether a person has been exposed to any of the four dengue virus serotypes, as well as Zika virus. The test is an enzyme immunoassay similar to ELISA, a platform widely used in laboratory testing throughout Brazil. The technology can easily be adapted for use in automated systems and rapid point-of-care tests. The study was conducted at the University of São Paulo's Biomedical Sciences Institute (ICB-USP) in partnership with researchers at the same university's medical school (FM-USP), and collaborators at the Federal University of West Bahia (UFOB) led by Jaime Henrique Amorim. An article reporting the findings is published in the Journal of Medical Virology.

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Scientists discover the function of a mysterious HIV component
IDW

Researchers from the Max Planck Institute of Biochemistry have discovered the mechanism behind an important step in the life cycle of HIV. Working together with teams at Heidelberg and Yale Universities, they found that the enigmatic "spacer peptide 2," one of the virus components, plays a key role in converting immature HIV-1 particles into infectious particles. The results of the study were published in the journal Nature.

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Hypertension, diabetes on the rise in T, early screening reveals alarming stats
The Times of India

Nearly 25 lakh people over the age of 30 have been diagnosed with hypertension, and around 12 lakh people have been identified with diabetes in Telangana through regular screenings under the NP-NCD.

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In a 1st in India, bird flu detected in domestic cats
MSN

The first cases of avian influenza virus (H5N1) in domestic cats in India were reported from Chhindwara district in Madhya Pradesh, raising concerns about the bird flu pathogen mutating and infecting humans.

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Scientists develop new natural killer cell strategy to target HIV
The Wistar Institute

Researchers at The Wistar Institute's HIV Cure and Viral Diseases Center have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. Wistar scientists have labeled this new approach "NuKES": Natural Killer Enhancement Strategy.

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Biomarker panel offers hope for early pancreatic cancer detection
Trinity College Dublin

Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13 percent of patients who are diagnosed with PC surviving for 5 years or more after initial diagnosis. In Ireland, there are approximately 900 cases of PC per year, and 820 PC-related deaths. Early detection of PC is the primary concern of most PC research, as it has the potential to make a substantial difference to the treatment and survival of patients

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How brain trauma triggers Alzheimer's disease: Study
ANI News

A study reveals that traumatic brain injury alters the small vessels in the brain, resulting in an accumulation of amyloid beta -- a hallmark of Alzheimer's disease. The findings suggest that vascular dysfunction could be an early driver in neurodegenerative disorders rather than being caused by neuronal damage.

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COVID-19 severity may be predicted by White Blood Cell count: Study
ANI News

A COVID-19 diagnosis is no longer as frightening as it used to be, thanks to developments in treatment choices. However, a new study reveals that leukocyte (white blood cell) count may now be used to identify who is more likely to develop more significant disease symptoms.

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C. Jejuni cause behind outbreak of GBS
The New Indian Express

The bacteria Campylobacter jejuni (C. jejuni) is being believed to be the cause behind the outbreak of Guillain-Barre Syndrome (GBS) in the regions of Maharashtra, mainly Pune, official sources said on Thursday. They said that bacteria Campylobacter jejuni has been found in 20-30 percent of the samples taken from the GBS positive cases. GBS mostly is a post-infection syndrome, which usually manifests itself two to six weeks after a person gets an infection. "Lot of samples have been taken and are being tested at the NIV Pune. Bacteria Campylobacter jejuni has been found in 20-30 percent of the samples taken from GBS positive cases and is believed to be the cause. But investigations are still on," a source said.

Health Services

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Cancer vaccine for women to be available in five to six months, says Union Minister Prataprao Jadhav
Deccan Herald

A vaccine to fight cancers affecting women will be available in five to six months, and those in the age group of 9 to 16 years will be eligible for inoculation, Union Minister Prataprao Jadhav said on Tuesday. The Union Minister of State for Health, Family Welfare and Ayush (Independent Charge) said that research on a vaccine is nearly complete and trials are underway. "The number of cancer patients has increased in the country, and the central government has initiated steps to address this issue. Women above 30 will undergo screening at hospitals, and daycare cancer centres will be established for early detection of the disease," Jadhav said.

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Govt to introduce AI in ICUs to enhance patient care
The Pioneer

Under the leadership of Chief Minister Yogi Adityanath, state-of-the-art arrangements are being meticulously planned for the upcoming Maha Kumbh to welcome devotees from across India and abroad. Among the latest initiatives, the government is set to introduce artificial intelligence (AI) in Intensive Care Units, aiming to enhance the quality of patient care and ensure a superior healthcare experience during the event. Being deployed for the first time within the Mela grounds, the advanced AI messaging flow system is capable of interpreting and conveying the concerns of patients from any part of the country or the world to doctors.

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Kerala to release Mpox prevention guidelines after man tests positive for fast-spreading Clade 1b strain
The New Indian Express

It has been identified that the 38-year-old man from Edavanna in Malappuram--who is under treatment for mpox--is infected with the Clade 1b strain of the virus, making him the first such case in the country. Top officials of the health department were tight-lipped about the test result. A statement from Health Minister Veena George regarding the test result is expected on Tuesday. She has convened a meeting of a state-level Rapid Response Team (RRT) to assess the situation when mpox cases increase. Clade 1b strain of the virus is more infectious than Clade 2 and it is currently behind the global outbreak.

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WHO highlights safe diagnosis during global campaign for patient safety
Pharma Biz

Recognizing the urgent need for a broad-based effort globally to reduce errors in medical diagnosis, the World Health Organization (WHO) is calling on all stakeholders to “Get it right, make it safe!” as part of the World Patient Safety Day campaign on 17th September. The theme ‘improving diagnosis for patient safety’ was selected in consultation with a wide range of stakeholders – from patients to policy-makers – to highlight how everyone has a vital role to play in reducing the risks and impact of errors in diagnosis.

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NIMHANS works to challenge mental health stigma, prioritizes ease access to care with empathy
Pharma Biz

National Institute of Mental Health and Neuro Sciences (NIMHANS) is ensuring to make mental health care more relatable and accessible. The Institute which plays a crucial role in challenging mental health stigma and advocating for a society that prioritizes mental well-being is making to normalize conversations about mental health.

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Health Ministry approves introduction of new shorter, more efficacious treatment regimen for drug-resistant TB in India
ANI News

Under the vision of the Prime Minister to rid the country of TB by 2025, five years ahead of the global target for eliminating the disease under the Sustainable Development Goals, the Union Ministry of Health and Family Welfare has approved the introduction of the BPaLM regimen, an official statement said. The BPaLM regimen is a novel treatment for multi-drug-resistant tuberculosis (MDR-TB) under its National TB Elimination Programme (NTEP) as a highly effective and shorter treatment option.

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Uttar Pradesh generated majority tokens under NHA's digital OPD scheme
The Feature Times

Of the over 47 million digital out-patient department (OPD) registrations under the National Health Authority’s (NHA’s) ‘scan and share’ service in the last two years, 12.4 million OPD tokens were generated by Uttar Pradesh alone.

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KITES Senior Care unveils new geriatric care centre in Bengaluru
Express Healthcare

KITES Senior Care, a division of Lifebridge Senior Care, founded by Rajagopal G, Dr A S Arvind, and Dr Reema Nadig, has launched a new Geriatric Care Centre on Kanakapura Road, Bengaluru. The centre will offer seniors, personalised transitional and rehab care to support their recovery after surgery, palliative and hospice care focused on comfort and pain management, and dependable respite care.

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Redcliffe Labs launches MPOX testing, strengthens national preparedness
BioSpectrum

Noida-based startup Redcliffe Labs, a purpose-driven PAN India diagnostic service provider, has announced the launch of its advanced MPOX testing capabilities, reinforcing its commitment to national health security. This strategic move is a significant step towards bolstering the nation’s preparedness against potential MPOX outbreaks.

Industry

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Researchers advance cost-effective diagnostics for antibiotic-resistant H. pylori
East Mojo

Researchers have introduced a novel diagnostic method for identifying Helicobacter pylori (H. pylori) and its antibiotic-resistance mutations, offering a cost-effective solution for patients in rural areas with limited access to diagnostic facilities. This advancement, developed using CRISPR-based technologies, holds promise for addressing global health challenges posed by the bacterium. H. pylori infections affect over 43 percent of the global population and are associated with a range of gastrointestinal conditions, including peptic ulcers, gastritis, dyspepsia, and gastric cancer. A significant challenge in managing these infections is resistance to clarithromycin, driven by specific mutations in the bacterium’s 23S ribosomal RNA gene. Such resistance often necessitates repeated diagnostic tests and multiple antibiotic treatments, complicating eradication efforts.

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Researchers at IIT-B develop needle-free shock syringes for painless treatments
The Indian Express

As an answer to the fear of needle-syringes, a team of researchers at Indian Institute of Technology (IIT) Bombay have developed a shock syringe, which doesn’t rely on piercing the skin with a sharp tip. Instead, it uses high-energy pressure waves (shock waves) that can travel faster than the speed of sound to pierce the skin. The team  led by Prof. Viren Menezes from the Department of Aerospace Engineering in their study published in the Journal of Biomedical Materials & Devices, the IIT Bombay researchers compared the effectiveness of drug delivery by a shock syringe versus a regular needle on laboratory rats. The team explained, “These waves, when generated, compress the surrounding medium (such as air or liquid) through which they travel. A similar effect happens during a sonic boom; when an aircraft flies faster than the speed of sound, it creates shockwaves that push and disturb the air.”

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NPPA issues revised calculation sheet for ceiling price of antibiotic injection following review order
Pharma Biz

The National Pharmaceutical Pricing Authority (NPPA) has released the revised calculation sheet for the ceiling price of antibiotic combination amoxicillin 1000 mg + clavulanic acid 200 mg power of injection following a review order from the Department of Pharmaceuticals (DoP). The review order was issued on October 4, in favour of an application filed by Cipla Ltd. The revised calculation sheet shows the price of Rs 141.65 per vial, as compared to the current ceiling price of Rs 140.66 per vial, notified in March 26, 2024. The price revision is after including the updated Price to retailer (PTR) of Rs 111.52 for Advent 1.2 mg injection powder.

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Fujifilm unveils medical training simulator designed to revolutionise endoscopy education
BioSpectrum

Fujifilm India, a leader in medical technology, has unveiled the groundbreaking mikoto Colon Model, a cutting-edge endoscopy simulation technology, during the Indian Association of Gastrointestinal Endosurgeons (IAGES) Prof. Dr. B Krishna Rau Simulation Training Programme, a hands-on endoscopy workshop, in Chennai.

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In a first, IIT Madras releases most detailed 3D high-resolution images of fetal brain
The Telegraph

The Indian Institute of Technology (IIT), Madras has become the first research organisation in the world to release the most detailed 3D high-resolution images of the fetal brain, Director V Kamakoti said on Tuesday. The key applications of generating such high-resolution brain images are advancements to current fetal imaging technologies for early diagnosis and treatment of developmental disorders. The pioneering work by the Sudha Gopalakrishnan Brain Centre of IIT Madras pushes the frontiers of Brain Mapping Technology and places India in the global league of brain mapping science as this is a first-of-its-kind work anywhere in the world, he said.

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Honeywell introduces liquid flow sensing solution to improve medication delivery for patients and clinicians
Express Healthcare

Honeywell has introduced a new liquid flow sensing platform designed and developed to increase the accuracy of dosing liquid medications and improve the treatment process for patients.

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Stryker launches 1788, next generation of advanced surgical camera in India
BioSpectrum

US-based Stryker, a global leader in medical technologies, has announced the launch of its groundbreaking 1788 Advanced Imaging Platform in India, continuing its legacy of excellence in surgical visualisation. The 1788 platform is Stryker’s most comprehensive and sophisticated surgical visualisation system to date, designed for use across multiple specialties and providing surgeons with enhanced imaging capabilities for improved patient outcomes.

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India will see an addition of over 22,000 hospital beds in private hospitals over next 3-5 years
ANI News

Growing incidence of lifestyle diseases and easing demand for affordable health care delivery are driving the healthcare market in India. A recent report by HSBC Global research on India hospitals says seven listed hospitals will add 14,000 beds in the next 3-5 years. A total of 22,000 new beds is expected, including those by other private hospital chains.

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World Patient Safety Day: WHO calls for global action to reduce diagnostic errors
PTI News

On the eve of World Patient Safety Day, the World Health Organization (WHO) urged all stakeholders to commit to reducing diagnostic errors and improving patient safety. The WHO emphasised that delayed, incorrect, or missed diagnoses can prolong illness and, in some cases, result in disability or even death. World Patient Safety Day, observed annually on September 17, was established by the WHO in 2019 following the adoption of resolution WHA72.6 by the World Health Assembly.

Doctors & Hospitals

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Tata Memorial Hospital advises cancer patients to shun 'unproven remedies'
The Tribune

Cancer patients should not delay or stop their treatment by following unproven remedies, oncologists at Tata Memorial Hospital said after former India cricketer Navjot Singh Sidhu claimed at a presser that his wife Navjot Kaur defeated stage 4 cancer with dietary and lifestyle changes. In a statement posted on X, the Director of Tata Memorial Hospital, Dr C S Pramesh, said, "Parts of the video imply that starving the cancer by not eating dairy products and sugar, consuming haldi (turmeric) and neem helped cure her 'incurable' cancer." These comments have no high quality evidence to support them, the statement signed by 262 oncologists from the Tata Memorial Hospital, both past and present, said.

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AIIMS Delhi Treats First Patient in GRASSROOT Trial for Treatment of Stroke Clots
Deccan Herald

Delhi AIIMS has launched the GRASSROOT (Gravity Stent-Retriever System for Reperfusion of Large Vessel Occlusion Stroke Trial) clinical trial to evaluate the safety and efficacy of an advanced brain stent for treatment of stroke clots particularly in Indian population. The study went live for enrolment on August 15 and the first patient was successfully treated on August 25. Subsequently, the patient was discharged from hospital, said Dr Shailesh Gaikwad, Professor and Head of Department of Neuroimaging and Intervential Neuroradiology at Neurosciences Centre, All India Institute of Medical Sciences (AIIMS), Delhi. The GRASSROOT trial is the first-ever study in India to test a novel next generation brain stent designed for Indian and Asian healthcare scenarios.

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Yashoda Medicity introduces advanced radiation oncology technologies
Express Healthcare

Yashoda Medicity, a new healthcare facility by Yashoda Foundations in Indirapuram, has introduced three advanced technologies in its Radiation Oncology department, positioning itself as a leader in cancer treatment and care in the region. The adoption of these technologies makes Yashoda Medicity the only hospital in Southeast Asia equipped with such equipment.

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Wockhardt Hospitals hosted Cyclothon Season 3 to promote heart health ahead of World Heart Day
Express Healthcare

Wockhardt Hospitals, Mira Road, organised the third season of its Cyclothon on September 1st, attracting more than 1,200 cyclists from across Mumbai, including major cycling groups. The event was held to raise awareness about heart health ahead of World Heart Day, which falls on September 29, 2024. Participants cycled through a 30 km and 15 km route across Uttan-Gorai Island, promoting fitness and heart health.

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Rise in joint pain among young adults post-dengue recovery, say doctors
VIO

A growing number of Bengalureans, especially younger individuals, are reporting persistent joint pain long after recovering from dengue, causing concern among medical experts. Although they test negative for the virus, these patients experience severe joint discomfort, a symptom that was absent during their illness. Doctors are now investigating whether a mutation in the dengue virus may be responsible for this unexpected development, raising concerns about its impact on the city's youth.

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HCMCT Manipal Hospital, Dwarka collaborates with Pfizer to launch CoE for adult vaccination
BioSpectrum

In a country where vaccination is often associated only with childhood immunisation and the need for adult vaccines is often overlooked, HCMCT Manipal Hospital and Pfizer India have collaborated to launch a dedicated Centre for adult vaccination at HCMCT Manipal Hospital, Dwarka, New Delhi, strengthening the delivery of adult vaccines.

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TN Doctors Highlight Life-Saving Potential of Simple Urine Dipstick Test
VOH

A urine dipstick test, a simple and cost-effective diagnostic tool, can significantly prevent complications such as organ failure, heart attacks, and premature deaths, particularly among those with hypertension and diabetes, according to a newly released report by the Tamil Nadu Public Health Department. Doctors analyzed data from 5.7 million people across Tamil Nadu who took the test between July 2023 and May 2024 as part of a state ‘urine dipstick testing program’ for the early detection of chronic kidney disease (CKD). The test was administered at all primary health centers and health sub-centers for individuals with diabetes and hypertension. The urine dipstick test, recommended during routine check-ups or when urinary tract infection, kidney disease, or diabetes is suspected, involves dipping a plastic stick with chemically treated pads into a urine sample. The results revealed that 13,082 patients had high levels of albumin, an important indicator of kidney damage.

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Dengue can seriously affect your brain, nervous system: Doctors
The Tribune

Although dengue is known to cause mild flu-like symptoms, the mosquito-borne viral illness has profound neurological implications that are often overlooked, said experts on Tuesday. Amid the monsoon in India, dengue cases have spiralled in various parts of the country, including Karnataka, Kerala, Telangana, Andhra Pradesh, Odisha, Delhi and Maharashtra. According to the latest data from the Municipal Corporation of Delhi (MCD), there have been 246 dengue cases in the national capital till June 30 this year. During the same period in 2023, Delhi saw only 122 cases, 143 cases in 2022, 36 cases in 2021, and 20 cases in 2020.

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Health experts stress the need for adult vaccination during World Immunisation Week
The New Indian Express

From polio to the coronavirus, vaccines play a pivotal role in protecting human health against a range of perilous diseases. As researchers strive to comprehend viruses and innovate new vaccines, it’s imperative to emphasise the significance of immunisation. Hence, World Immunisation Week is observed annually from April 24 to 30. During this week, let’s explore the significance of both traditional and emerging vaccines that are essential for everyone.

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