The baby was brought to Fortis Escorts Heart Institute, Okhla, in a serious condition with breathing difficulties, sepsis-like symptoms, heart failure signs, elevated heart rate, excessive perspiration, inability to feed, liver enlargement, and failure to gain weight. An echocardiogram revealed that the baby suffered from a hole in the heart, also known as patent ductus arteriosus (PDA) — a condition where an extra blood vessel is found in babies before birth and just after birth.
Amidst concerns over the outbreak of deadly virus infections like Nipah in Kerala, the state on Monday reported a rare case of recovery from amoebic meningoencephalitis, which has a 97 percent mortality rate. State Health Minister Veena George's office on Monday confirmed that it was a rare occurrence, which has a mortality rate of 97 percent and it is believed that only 11 persons in the world so far recovered from the infection. Earlier detection of the infection helped in speedy recovery of the boy. The minister also praise the efforts of the medical team that treated the boy.
For the first time, scientists have grown 3D brain models using cells from multiple people. The new hybrid creations, which researchers have dubbed "chimeroids," are a variation of brain organoids — tiny 3D models made of tissue that mimic the structure and function of a full-size brain. These models are more accurate to human biology than 2D cellular models or animals like lab mice. Because of this, scientists hope that the models will accelerate drug research and development.
Ten years ago, a scan showed that I had torn the meniscus in my knee. The pain was bad and I was limping a lot of the time. My doctor recommended arthroscopic knee surgery to fix it. Being scared of scalpels, I asked whether there were other options. He said I could try physiotherapy, but that it was unlikely to work. I tried the physio and did the recommended exercises diligently, and my knee pain and function returned to almost normal. I even ran my first (and only) marathon a year later.
A small farmer from a remote village walks into the nearest town’s health clinic. He breathes into a tube connected to a Vionix analyser. This device compares the farmer’s breath with hundreds of millions of other samples from around the world. An AI model, running on the cloud, identifies patterns of disease manifestations in the spectral signatures of the breath sample and instantly provides results on the farmer’s smartphone.
The first man to receive a genetically modified pig kidney transplant has died two months after the operation, the hospital which carried out the procedure has said. Richard "Rick" Slayman, 62, was suffering with end-stage kidney disease before undergoing the operation in March. Massachusetts General Hospital (MGH) said on Sunday there was no indication his death was a result of the transplant.
A girl born deaf can now hear unaided after participating in a world-first trial. The CHORD study is for children born with hearing loss due to a genetic condition called auditory neuropathy. Auditory neuropathy is a condition where the ear can detect sound normally, but has a problem sending signals to the brain.
A study found that one-third of patients receiving surgery for adult spinal deformity (ASD) also have severe hip osteoarthritis (OA), which can lead to poor spinal alignment and physical functionality. Findings of the study published in The Journal of Bone & Joint Surgery.
For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, but they come with an amplified risk for developing dementia in the future. The glaring absence of treatments for such a widespread condition drove a team of scientists at Gladstone Institutes to uncover, on a molecular level, how traumatic brain injuries trigger neurodegeneration—and just as importantly, how to target that process to prevent long-term damage.
Sapience Therapeutics announced that the first patient has been enrolled in its phase 2 dose expansion study evaluating ST316, the company’s first-in-class antagonist of ß-catenin. Enrollment of the study’s phase 1 monotherapy dose escalation portion was completed in July 2024.
Researchers have identified nearly 200 chemicals linked to breast cancer in food packaging materials and plastic tableware, with many capable of migrating into the human body. In a study published in ‘Frontiers in Toxicology’, they highlighted the presence of at least 189 potential breast carcinogens, including PFAS, bisphenols, and phthalates, in food contact materials (FCMs). Jane Muncke, study co-author, managing director and chief scientific officer at the Food Packaging Forum, a non-profit foundation based in Zurich, Switzerland said, “There is strong evidence that 76 known or potential breast carcinogens from food contact materials recently purchased all over the world can be found in people.”
British drugmaker GSK said on Wednesday its experimental herpes simplex virus (HSV) vaccine candidate failed to meet the main goal of a mid-stage trial and would not be taken forward to a late-stage trial.
A pooled analysis from the BOREAS and NOTUS phase 3 studies showed that Dupixent reduced exacerbations and improved lung function compared to placebo in adults with uncontrolled chronic obstructive pulmonary disease (COPD) and evidence of type 2 inflammation (i.e., raised blood eosinophils).
Positive results from the HERCULES phase 3 study showed that tolebrutinib, Sanofi’s oral brain-penetrant BTK inhibitor, met the primary endpoint of improvement over placebo in delaying time to onset of confirmed disability progression (CDP) in people with non-relapsing secondary progressive MS (nrSPMS).
This WHO Medical Product Alert refers to one batch of falsified Oxymorphone Hydrochloride 40mg. The falsified product was detected in the unregulated supply chain in Finland and reported to WHO in July 2024 by the Finnish Medicines Agency (FIMEA). Oxymorphone Hydrochloride is a semi-synthetic opioid used to treat moderate to severe pain. However, laboratory analysis of samples of the falsified product found that the tablets contained metonitazene instead.
Merck announced positive topline results from its phase 2b/3 clinical trial (MK-1654-004) evaluating clesrovimab (MK-1654), the company’s investigational prophylactic monoclonal antibody designed to protect infants from respiratory syncytial virus (RSV) disease.
The UK will become the first country in the world to have a national programme that uses the same vaccine to protect both newborns and older adults against respiratory syncytial virus (RSV).
Roche announced that it has received the CE Mark for its Accu-Chek SmartGuide continuous glucose monitoring (CGM) solution.
It has been identified that the 38-year-old man from Edavanna in Malappuram--who is under treatment for mpox--is infected with the Clade 1b strain of the virus, making him the first such case in the country. Top officials of the health department were tight-lipped about the test result. A statement from Health Minister Veena George regarding the test result is expected on Tuesday. She has convened a meeting of a state-level Rapid Response Team (RRT) to assess the situation when mpox cases increase. Clade 1b strain of the virus is more infectious than Clade 2 and it is currently behind the global outbreak.
Recognizing the urgent need for a broad-based effort globally to reduce errors in medical diagnosis, the World Health Organization (WHO) is calling on all stakeholders to “Get it right, make it safe!” as part of the World Patient Safety Day campaign on 17th September. The theme ‘improving diagnosis for patient safety’ was selected in consultation with a wide range of stakeholders – from patients to policy-makers – to highlight how everyone has a vital role to play in reducing the risks and impact of errors in diagnosis.
National Institute of Mental Health and Neuro Sciences (NIMHANS) is ensuring to make mental health care more relatable and accessible. The Institute which plays a crucial role in challenging mental health stigma and advocating for a society that prioritizes mental well-being is making to normalize conversations about mental health.
Under the vision of the Prime Minister to rid the country of TB by 2025, five years ahead of the global target for eliminating the disease under the Sustainable Development Goals, the Union Ministry of Health and Family Welfare has approved the introduction of the BPaLM regimen, an official statement said. The BPaLM regimen is a novel treatment for multi-drug-resistant tuberculosis (MDR-TB) under its National TB Elimination Programme (NTEP) as a highly effective and shorter treatment option.
Of the over 47 million digital out-patient department (OPD) registrations under the National Health Authority’s (NHA’s) ‘scan and share’ service in the last two years, 12.4 million OPD tokens were generated by Uttar Pradesh alone.
KITES Senior Care, a division of Lifebridge Senior Care, founded by Rajagopal G, Dr A S Arvind, and Dr Reema Nadig, has launched a new Geriatric Care Centre on Kanakapura Road, Bengaluru. The centre will offer seniors, personalised transitional and rehab care to support their recovery after surgery, palliative and hospice care focused on comfort and pain management, and dependable respite care.
Noida-based startup Redcliffe Labs, a purpose-driven PAN India diagnostic service provider, has announced the launch of its advanced MPOX testing capabilities, reinforcing its commitment to national health security. This strategic move is a significant step towards bolstering the nation’s preparedness against potential MPOX outbreaks.
Nearly 20 months after a recommendation by the World Health Organization (WHO), India has finally begun to take steps for introducing an advanced, short-term treatment regimen to tackle multi-drug resistant tuberculosis, hoping for a quick remission for thousands of such drug resistant patients.
Health Minister J P Nadda announced on Friday that the Central government is actively considering the inclusion of the Human Papillomavirus (HPV) vaccine in the national immunization program.
US-based Stryker, a global leader in medical technologies, has announced the launch of its groundbreaking 1788 Advanced Imaging Platform in India, continuing its legacy of excellence in surgical visualisation. The 1788 platform is Stryker’s most comprehensive and sophisticated surgical visualisation system to date, designed for use across multiple specialties and providing surgeons with enhanced imaging capabilities for improved patient outcomes.
Growing incidence of lifestyle diseases and easing demand for affordable health care delivery are driving the healthcare market in India. A recent report by HSBC Global research on India hospitals says seven listed hospitals will add 14,000 beds in the next 3-5 years. A total of 22,000 new beds is expected, including those by other private hospital chains.
On the eve of World Patient Safety Day, the World Health Organization (WHO) urged all stakeholders to commit to reducing diagnostic errors and improving patient safety. The WHO emphasised that delayed, incorrect, or missed diagnoses can prolong illness and, in some cases, result in disability or even death. World Patient Safety Day, observed annually on September 17, was established by the WHO in 2019 following the adoption of resolution WHA72.6 by the World Health Assembly.
Excessive and improper use of antibiotics is taking a significant toll on the health of Indians. A recent study published in The Lancet revealed that bacterial infections were responsible for 60 percent of the 2.99 million sepsis-related deaths in the country in 2019. Of these, around 1.04 million sepsis deaths (33.4 percent) were associated with bacterial antimicrobial resistance (AMR), with 290,000 deaths directly attributed to it. Sepsis occurs when the immune system responds dangerously to a bacterial infection, and without timely treatment, it can result in organ failure. Antimicrobial resistance (AMR) is already a significant global health issue and is expected to escalate in the coming years.
The National Pharmaceutical Pricing Authority (NPPA) has notified the retail price of 62 new drugs following its latest meeting, while deferring price fixation of three formulations based on representations from the companies. The Authority has also notified extension of ceiling prices of orthopaedic knee implants for knee replacement system for one more year till September 15, 2025, observing that the existing ceiling prices have contributed to increased access to affordable healthcare to the general public.
Days after Entod Pharmaceuticals’ claim that its eye drop can reduce dependency on reading glass, the Drug Controller General of India (DCGI) has suspended the permission granted to Entod Pharmaceuticals to make and sell the product. In an order, issued on 10 September, the DCGI said the company did not obtain approval from the Central Licencing Authority to make such claims for the product. It also stated that it has held the pharma company in violation of the permission to manufacture the ophthalmic solution under the New Drugs and Clinical Trial Rules, 2019.
It may be time to take another look at your diet: a new study suggests that two-thirds of the people on the planet are falling short when it comes to getting four key vitamins and minerals from their food and drink. The researchers behind the study, from the Harvard TH Chan School of Public Health, the University of California, Santa Barbara (UCSB), and the Global Alliance for Improved Nutrition (GAIN), say it's a wake-up call for global health.
The World Health Organization (WHO) on Wednesday announced that it has published a global framework to help Member States comprehensively investigate the origins of new and re-emerging pathogens. The framework has been published with the support of the Scientific Advisory Group for the Origins of Novel Pathogens (SAGO). While there are a number of tools available for investigating infectious disease outbreaks, this is the first unified, structured approach to investigating the origins of a novel pathogen, WHO said in a statement. This framework aims to fill that gap by providing a comprehensive set of scientific investigations and studies. It is the first version of a “how-to” guide that will be updated as and when needed, based on feedback from users, it added.
India is set to host the 15th World Conference on Injury Prevention and Safety Promotion, 2024 — “Safety 2024” from September 2 to 4 with focus on global efforts in areas such as road safety and drowning prevention.
Delhi AIIMS has launched the GRASSROOT (Gravity Stent-Retriever System for Reperfusion of Large Vessel Occlusion Stroke Trial) clinical trial to evaluate the safety and efficacy of an advanced brain stent for treatment of stroke clots particularly in Indian population. The study went live for enrolment on August 15 and the first patient was successfully treated on August 25. Subsequently, the patient was discharged from hospital, said Dr Shailesh Gaikwad, Professor and Head of Department of Neuroimaging and Intervential Neuroradiology at Neurosciences Centre, All India Institute of Medical Sciences (AIIMS), Delhi. The GRASSROOT trial is the first-ever study in India to test a novel next generation brain stent designed for Indian and Asian healthcare scenarios.
Yashoda Medicity, a new healthcare facility by Yashoda Foundations in Indirapuram, has introduced three advanced technologies in its Radiation Oncology department, positioning itself as a leader in cancer treatment and care in the region. The adoption of these technologies makes Yashoda Medicity the only hospital in Southeast Asia equipped with such equipment.
Wockhardt Hospitals, Mira Road, organised the third season of its Cyclothon on September 1st, attracting more than 1,200 cyclists from across Mumbai, including major cycling groups. The event was held to raise awareness about heart health ahead of World Heart Day, which falls on September 29, 2024. Participants cycled through a 30 km and 15 km route across Uttan-Gorai Island, promoting fitness and heart health.
A growing number of Bengalureans, especially younger individuals, are reporting persistent joint pain long after recovering from dengue, causing concern among medical experts. Although they test negative for the virus, these patients experience severe joint discomfort, a symptom that was absent during their illness. Doctors are now investigating whether a mutation in the dengue virus may be responsible for this unexpected development, raising concerns about its impact on the city's youth.
In a country where vaccination is often associated only with childhood immunisation and the need for adult vaccines is often overlooked, HCMCT Manipal Hospital and Pfizer India have collaborated to launch a dedicated Centre for adult vaccination at HCMCT Manipal Hospital, Dwarka, New Delhi, strengthening the delivery of adult vaccines.
A urine dipstick test, a simple and cost-effective diagnostic tool, can significantly prevent complications such as organ failure, heart attacks, and premature deaths, particularly among those with hypertension and diabetes, according to a newly released report by the Tamil Nadu Public Health Department. Doctors analyzed data from 5.7 million people across Tamil Nadu who took the test between July 2023 and May 2024 as part of a state ‘urine dipstick testing program’ for the early detection of chronic kidney disease (CKD). The test was administered at all primary health centers and health sub-centers for individuals with diabetes and hypertension. The urine dipstick test, recommended during routine check-ups or when urinary tract infection, kidney disease, or diabetes is suspected, involves dipping a plastic stick with chemically treated pads into a urine sample. The results revealed that 13,082 patients had high levels of albumin, an important indicator of kidney damage.
Although dengue is known to cause mild flu-like symptoms, the mosquito-borne viral illness has profound neurological implications that are often overlooked, said experts on Tuesday. Amid the monsoon in India, dengue cases have spiralled in various parts of the country, including Karnataka, Kerala, Telangana, Andhra Pradesh, Odisha, Delhi and Maharashtra. According to the latest data from the Municipal Corporation of Delhi (MCD), there have been 246 dengue cases in the national capital till June 30 this year. During the same period in 2023, Delhi saw only 122 cases, 143 cases in 2022, 36 cases in 2021, and 20 cases in 2020.
From polio to the coronavirus, vaccines play a pivotal role in protecting human health against a range of perilous diseases. As researchers strive to comprehend viruses and innovate new vaccines, it’s imperative to emphasise the significance of immunisation. Hence, World Immunisation Week is observed annually from April 24 to 30. During this week, let’s explore the significance of both traditional and emerging vaccines that are essential for everyone.
Sunrise Oncology Centre, a leading provider of comprehensive cancer care, announced the opening of its new facility in Vasai, marking the establishment of the first cancer registry in Palghar district. The new centre aims to provide holistic and internationally guided cancer treatments, including core systemic therapies like chemotherapy and immunotherapy, as well as essential supportive care services.
A multitude of genes have been linked to the development of Alzheimer's disease. Specifically how those genes might influence the progression of neurodegeneration remains something of a black box though, in part because of the challenges of examining in molecular detail the brain of a living patient. Using cerebrospinal fluid (CSF) collected from living patients, a team of researchers at Washington University School of Medicine in St. Louis has for the first time linked disease-related proteins and genes to identify specific cellular pathways responsible for Alzheimer's genesis and progression. Because these proteins were gathered from CSF, they are a good proxy for activity in the brain, and several of them may be potential targets for therapies.
A collaboration of researchers led by Emory University Rollins School of Public Health, Atlanta, is urging caution when prescribing off-label glucose-lowering drugs to individuals with type 1 diabetes (T1D). Both glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter 2 (SGLT2) inhibitors have shown significant benefits for cardiovascular and renal health in other populations, particularly in patients with type 2 diabetes. GLP-1RAs are also known for their weight loss effects.
The diabetes drug semaglutide, also known as Ozempic, has a positive effect on patients with chronic kidney disease and obesity. The amount of protein in their urine decreased, as did the degree of inflammation of their kidneys and their blood pressure. This was shown in an international study led by clinical pharmacologist Hiddo L. Heerspink of the University Medical Center Groningen in the Netherlands. This is the first time that it has been shown that this diabetes drug, now best known as a means of losing weight, is also effective for patients with chronic kidney damage.
Amid the growing use of weight loss medications, a new study has raised concerns about declining skeletal muscle health caused by the popular drugs. In a recent commentary published in The Lancet journal, researchers from the US and Canada highlighted the critical importance of skeletal muscle mass in the context of medically induced weight loss, particularly with the widespread use of GLP-1 receptor agonists.
Researchers at the Case Western Reserve School of Medicine have found that when compared to seven other anti-diabetic drugs, semaglutide, a popular diabetes and weight-loss drug, may lower the risk of Alzheimer's disease in people with type 2 diabetes (T2D).
Metformin, a drug traditionally used to treat type 2 diabetes, has garnered significant attention for its potential anti-aging effects. Its mechanism involves improving insulin sensitivity, reducing inflammation and promoting cellular repair processes, all important factors in aging. In this new research, experts in China, along with U.S. colleagues, have discovered that administering the diabetes drug metformin to cynomolgus monkeys can slow aging across multiple organs, including the brain. The study was carried out by teams from several institutions, including the Institute of Zoology and the Beijing Institute of Genomics, both part of the Chinese Academy of Sciences.
The latest report by India's medical panel has revealed a troubling rise in antibiotic resistance across the country. Some diseases, like urinary tract infections (UTIs), blood infections, pneumonia, and typhoid, are becoming harder to treat because the bacteria causing them are not responding to common antibiotics anymore. The Indian Council of Medical Research (ICMR)'s Antimicrobial Resistance Surveillance Network (AMRSN) released its annual report that focused on common antibiotics used to treat infections like pneumonia, sepsis, respiratory infections, and diarrhoea.
When researchers discovered enough proof that a medication used to treat bone marrow cancer and Kaposi sarcoma is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that affects 1 in 5,000 people worldwide, they decided to terminate an early clinical trial funded by the National Institutes of Health (NIH).
Adults who use the prescription drug metformin to treat their type 2 diabetes have a lower risk of developing long Covid or dying after a Covid-19 infection than people with diabetes who take other anti-diabetes medications, according to a large study supported by the National Institutes of Health (NIH).
Biological E Limited's Corbevax is being administered to children in the age group 12-14 in India. This age group got the Indian government's nod to be receive vaccine against the novel coronavirus from 16 March, Wednesday. These children have to register for getting the vaccine on the CoWIN portal. India's third indigenous anti-Covid vaccine has been manufactured by Hyderabad-based Biological E Limited. Biological E has supplied 5 crore doses of Corbevax to the Centre, which has then distributed the same to states.
Biological E seems confident regarding getting emergency use authorisation for use of its COVID vaccine Corbevax among children in the age group of 5-12 years. Currently, the vaccine is inoculated among children in the age group of 12 to 14 years The Hyderabad-based company Is qualified to produce around 1 billion dosages of Corbevax annually and it is geared up to meet any increase in demand. Currently, the company has produced 30 crore vaccines as part of its commitment made to the Government of India, with 5 crore dosages already supplied.
Biotech firm Biological E. Limited is geared to facilitate the first phase of the vaccination drive for the 12-15 age group and is ready with 30 crore doses of which five crore has been rolled out to 17 different sites in the country, said a top official of the firm. "This is the most affordable COVID-19 vaccine for the Government of India which is providing free vaccination to all eligible citizens. The pricing of CORBEVAX in the private market will be Rs 800 (and inclusive of all taxes and vaccine administration charges will cost Rs 990) The vaccine is being sold at Rs 145 per dose to the government," Mahima Datla, managing director of Biological E. Limited said at a virtual media interaction on Wednesday. "We have an annual production capacity upto one billion vaccines," Datla said. The firm collaborated with the Texas Children's Hospital and the Baylor College to develop Corbevax vaccine. Dynavax, Inc from USA supported Corbevax development by providing the adjuvant and THSTI Delhi conducted key immunogenicity testing as part of a comprehensive clinical trial development plan.
Only about 3,800 children aged between 12 and 14 were vaccinated against Covid-19 in the city on Wednesday, the first day of vaccination for this cohort in the country. All the children were administered Corbevax, India's first indigenously developed protein subunit vaccine against Covid-19, made by Biological E. Each dose in the private market will cost Rs 800 per dose, excluding GST, and around Rs 990, including taxes and administration charges. For the government, the price will be Rs 145. There are nearly 6.2 lakh children in this age group in Delhi who are eligible for the vaccine. Hospital officials said the first day saw a lukewarm response; footfall is expected to pick up after Holi.
The baby was brought to Fortis Escorts Heart Institute, Okhla, in a serious condition with breathing difficulties, sepsis-like symptoms, heart failure signs, elevated heart rate, excessive perspiration, inability to feed, liver enlargement, and failure to gain weight. An echocardiogram revealed that the baby suffered from a hole in the heart, also known as patent ductus arteriosus (PDA) — a condition where an extra blood vessel is found in babies before birth and just after birth.
Amidst concerns over the outbreak of deadly virus infections like Nipah in Kerala, the state on Monday reported a rare case of recovery from amoebic meningoencephalitis, which has a 97 percent mortality rate. State Health Minister Veena George's office on Monday confirmed that it was a rare occurrence, which has a mortality rate of 97 percent and it is believed that only 11 persons in the world so far recovered from the infection. Earlier detection of the infection helped in speedy recovery of the boy. The minister also praise the efforts of the medical team that treated the boy.
For the first time, scientists have grown 3D brain models using cells from multiple people. The new hybrid creations, which researchers have dubbed "chimeroids," are a variation of brain organoids — tiny 3D models made of tissue that mimic the structure and function of a full-size brain. These models are more accurate to human biology than 2D cellular models or animals like lab mice. Because of this, scientists hope that the models will accelerate drug research and development.
Ten years ago, a scan showed that I had torn the meniscus in my knee. The pain was bad and I was limping a lot of the time. My doctor recommended arthroscopic knee surgery to fix it. Being scared of scalpels, I asked whether there were other options. He said I could try physiotherapy, but that it was unlikely to work. I tried the physio and did the recommended exercises diligently, and my knee pain and function returned to almost normal. I even ran my first (and only) marathon a year later.
A small farmer from a remote village walks into the nearest town’s health clinic. He breathes into a tube connected to a Vionix analyser. This device compares the farmer’s breath with hundreds of millions of other samples from around the world. An AI model, running on the cloud, identifies patterns of disease manifestations in the spectral signatures of the breath sample and instantly provides results on the farmer’s smartphone.
The first man to receive a genetically modified pig kidney transplant has died two months after the operation, the hospital which carried out the procedure has said. Richard "Rick" Slayman, 62, was suffering with end-stage kidney disease before undergoing the operation in March. Massachusetts General Hospital (MGH) said on Sunday there was no indication his death was a result of the transplant.
A girl born deaf can now hear unaided after participating in a world-first trial. The CHORD study is for children born with hearing loss due to a genetic condition called auditory neuropathy. Auditory neuropathy is a condition where the ear can detect sound normally, but has a problem sending signals to the brain.
A study found that one-third of patients receiving surgery for adult spinal deformity (ASD) also have severe hip osteoarthritis (OA), which can lead to poor spinal alignment and physical functionality. Findings of the study published in The Journal of Bone & Joint Surgery.
For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, but they come with an amplified risk for developing dementia in the future. The glaring absence of treatments for such a widespread condition drove a team of scientists at Gladstone Institutes to uncover, on a molecular level, how traumatic brain injuries trigger neurodegeneration—and just as importantly, how to target that process to prevent long-term damage.
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